A procedure used prior to implantation, Pre-implantation genetic diagnosis (PGD) helps identify genetic defects within embryos created through In-Vitro Fertilization to prevent certain diseases or disorders from being passed on to the child.
It is undertaken as a testing process of embryos produced during a treatment cycle for particular genetic disorders before they are transferred to the woman partner’s uterus.
A single gene disorder results from a single mutated gene. According to experts, there are estimated to be over 4000 human diseases caused by single gene defects e.g., Huntington’s disease, Neurofibromatosis, Cystic Fibrosis and Sickle-Cell Anemia.
Currently, PGD is available for virtually all single gene disorders.
Pre-Implantation Genetic Diagnosis (PGD) starts with the process of In-Vitro Fertilization that includes egg retrieval and fertilization in a laboratory. Once done successfully, then over the next three days the embryo will divide into eight cells.
Pre-Implantation Genetic Diagnosis involves the following steps:
Once the whole of PGD procedure has been performed and embryos free of genetic problems have been identified, then the embryos are placed back in the woman’s uterus, and implantation will be attempted.
All additional embryos free of genetic problems are frozen for later use while embryos with the problematic genes are destroyed.
The benefits of PGD include:
Any couple who:
Such couples can undergo appropriate genetic counseling at Juhi Fertility Services (JFS), a premier Fertility Centre in Hyderabad. The Fertility Specialist in-conjunction with the scientific team at JFS will later determine if PGD can be done.
It must be remembered that no screening test is 100% accurate. As such, Genetic screening done at JFS by some of the best fertility specialists in Hyderabad and India, will only result in the woman-partner who becomes pregnant to undergo prenatal testing which will reveal whether the genetic diagnosis was correct, or not. Furthermore, it will also confirm whether or not the foetus is unaffected by the specific disease or mutation.
For world-class Pre-Implantation Genetic Diagnosis (PGD) in Hyderabad, there is no better choice than Juhi Fertility Centre, a leading Fertility Clinic in Hyderabad.
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